Ask Dr. Mona: Hormone replacement therapy in younger peri-menopausal women
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HRT for 10 years appears to cut risk of heart failure and heart attack without increasing cancer, deep venous thrombosis or stroke
Women who take hormone replacement therapy (HRT) for 10 years after menopause may have a significantly reduced risk of mortality, heart failure and heart attack without any increased risk of cancer, deep venous thrombosis or stroke, according to a study in the British Medical Journal.
Danish researchers carried out a randomized trial over 10 years with six years of additional follow-up on 1,006 white, healthy, recently menopausal women age 45 to 58. In the study, 504 received hormone replacement therapy and 502 didn't.
After 10 years, 16 women in the treatment group had either died of or were hospitalized for a heart attack or experienced heart failure, compared to 33 in the control group. Deaths were 15 in the treatment group compared with 26 in the control group.
There was no increase in any cancer or breast cancer associated with HRT. This effect lasted for the 16 years of treatment and follow-up. There were two cases of deep venous thrombosis in the treated group versus one in the control group. There were 11 strokes in the treatment group compared to 14 in the control group.
Researchers wrote:
"With the longest duration of randomized treatment and complete and long-term follow up, the present study provides a unique opportunity to study the clinical implications of long term hormone therapy started in young postmenopausal women within three to 24 months of menopause when randomized."
Tuesday, May 21 2013 1:18 PM EDT2013-05-21 17:18:01 GMT
What a thrill to be invited as one of only two American journalists and nine other international journalists on a medical journalism study tour of some of Poland's finest international medical tourism destinations.
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Wednesday, November 21 2012 11:11 AM EST2012-11-21 16:11:29 GMT
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Wednesday, November 7 2012 8:44 PM EST2012-11-08 01:44:12 GMT
12 members of our team were deployed to Brookdale University Medical Center to assist with an influx of patients from a nursing home that was devastated by the Superstorm Sandy.
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Wednesday, November 7 2012 7:31 PM EST2012-11-08 00:31:57 GMT
My official Deployment Activation orders came down from the Office of the Assistant Secretary for Preparedness & Response, Dept of Health and Human Services.
My official Deployment Activation orders came down from the Office of the Assistant Secretary for Preparedness & Response, Dept of Health and Human Services.
Wednesday, August 29 2012 2:31 PM EDT2012-08-29 18:31:06 GMT
As we wait and worry about the effects of Hurricane Isaac, I can't help but think back to almost exactly 7 years ago when my federal Disaster Medical Assistance Team was "boots to the ground" after Katrina.
As we wait and worry about the effects of Hurricane Isaac, I can't help but think back to almost exactly 7 years ago when my federal Disaster Medical Assistance Team was "boots to the ground" after Katrina.
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